Ege \u00dcniversitesi (E\u00dc) T\u0131p Fak\u00fcltesi\u00a0\u00c7ocuk Hematolojisi Bilim Dal\u0131\u00a0Ba\u015fkan\u0131 Prof. Dr. Kaan Kavakl\u0131,\u00a0ABD, \u0130ngiltere, Fransa ve Hindistan ile i\u015fbirli\u011fi i\u00e7inde\u00a0hemofili hastalar\u0131nda 2014 y\u0131l\u0131 i\u00e7inde gen \u00e7al\u0131\u015fmalar\u0131na\u00a0ba\u015flamay\u0131 planlad\u0131klar\u0131n\u0131 belirterek, “Gen tedavisi ba\u015far\u0131l\u0131 olursa hemofili hastalar\u0131n\u0131n \u00f6m\u00fcr boyu ila\u00e7 kullanmas\u0131 gerekmeyecek” dedi.<\/p>\n
Prof. Dr. Kavakl\u0131, hemofilinin,\u00a0kan\u0131n p\u0131ht\u0131la\u015fmas\u0131nda \u00f6nemli rol\u00fc bulunan\u00a0proteinlerin karaci\u011ferde salg\u0131lanamamas\u0131 nedeniyle\u00a0ortaya \u00e7\u0131kt\u0131\u011f\u0131n\u0131, hastal\u0131\u011f\u0131n\u00a0p\u0131ht\u0131la\u015fma bozuklu\u011fu yaratt\u0131\u011f\u0131n\u0131 anlatt\u0131.<\/p>\n
Genetik kaynakl\u0131 hemofili hastal\u0131\u011f\u0131n\u0131n tedavisinin bulunmad\u0131\u011f\u0131na dikkati \u00e7eken Kavakl\u0131, “Hemofili hastalar\u0131\u00a0kolayl\u0131kla kan\u0131yor, v\u00fccutlar\u0131nda\u00a0morluklar olu\u015fuyor,\u00a0eklem i\u00e7leri kan\u0131yor ve \u015fiddetli a\u011fr\u0131lar\u0131 oluyor. Hastalara,\u00a0kanamay\u0131 durdurmak ya da kanama \u00f6ncesi \u00f6nlem almak i\u00e7in karaci\u011ferde salg\u0131lanmayan fakt\u00f6r 8 proteininden\u00a0veriyoruz” diye konu\u015ftu.<\/p>\n
E\u00dc \u00c7ocuk Hastanesi Hemotoloji B\u00f6l\u00fcm\u00fc olarak, gen tedavisinin yap\u0131labilmesine y\u00f6nelik giri\u015fimlerde bulunduklar\u0131n\u0131\u00a0ifade eden Kavakl\u0131, \u015f\u00f6yle devam etti:<\/p>\n
“Hemofilide gen tedavisi yap\u0131labilir ve\u00a0bozuk olan gen d\u00fczeltilebilirse hastal\u0131kta kal\u0131c\u0131 bir iyile\u015fme sa\u011flanabilir. Gen tedavisinde\u00a0uzun s\u00fcredir hayvanlarla laboratuvar ortam\u0131nda deneyler yap\u0131l\u0131yordu. Hemofilinin bir tipinde 2 sene \u00f6nce insanda \u00e7al\u0131\u015fmalar ba\u015flad\u0131. ABD, \u0130ngiltere, Fransa ve Hindistan ve T\u00fcrkiye’den olu\u015fan grup ile do\u011fumsal fakt\u00f6r 8 eksikli\u011fi\u00a0Hemofili A hastalar\u0131nda 2014 y\u0131l\u0131 i\u00e7inde gen \u00e7al\u0131\u015fmalar\u0131na\u00a0ba\u015flamay\u0131 planl\u0131yoruz.”\u00a0<\/p>\n
Kavakl\u0131, gen tedavisinde kullan\u0131lacak, eksik olan genin y\u00fcklendi\u011fi ABD’de \u00fcretilen\u00a0partik\u00fcl\u00fcn, T\u00fcrkiye’ye gelece\u011fini\u00a0ve hastalara uygulayabileklerini kaydetti.(A.A)<\/p>\n","protected":false},"excerpt":{"rendered":"
Ege \u00dcniversitesi (E\u00dc) T\u0131p Fak\u00fcltesi\u00a0\u00c7ocuk Hematolojisi Bilim Dal\u0131\u00a0Ba\u015fkan\u0131 Prof. Dr. Kaan Kavakl\u0131,\u00a0ABD, \u0130ngiltere, Fransa ve Hindistan ile i\u015fbirli\u011fi i\u00e7inde\u00a0hemofili hastalar\u0131nda 2014 y\u0131l\u0131 i\u00e7inde gen \u00e7al\u0131\u015fmalar\u0131na\u00a0ba\u015flamay\u0131 planlad\u0131klar\u0131n\u0131 belirterek, “Gen tedavisi ba\u015far\u0131l\u0131 olursa hemofili hastalar\u0131n\u0131n \u00f6m\u00fcr boyu ila\u00e7 kullanmas\u0131 gerekmeyecek” dedi. Prof. Dr. Kavakl\u0131, hemofilinin,\u00a0kan\u0131n p\u0131ht\u0131la\u015fmas\u0131nda \u00f6nemli rol\u00fc bulunan\u00a0proteinlerin karaci\u011ferde salg\u0131lanamamas\u0131 nedeniyle\u00a0ortaya \u00e7\u0131kt\u0131\u011f\u0131n\u0131, hastal\u0131\u011f\u0131n\u00a0p\u0131ht\u0131la\u015fma bozuklu\u011fu yaratt\u0131\u011f\u0131n\u0131 anlatt\u0131. Genetik kaynakl\u0131 hemofili hastal\u0131\u011f\u0131n\u0131n tedavisinin[Devam\u0131n\u0131 Oku…]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22524],"tags":[22672,22666,22661,22671,22669],"_links":{"self":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13042"}],"collection":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/comments?post=13042"}],"version-history":[{"count":0,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13042\/revisions"}],"wp:attachment":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/media?parent=13042"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/categories?post=13042"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/tags?post=13042"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}