Poliovir\u00fcs denilen etkenlerle olu\u015fan beyin veya omurili\u011fin tutulmas\u0131yla karakterize olan ve fel\u00e7 veya \u00f6l\u00fcmle sonu\u00e7lanabilen bula\u015f\u0131c\u0131 bir hastal\u0131kt\u0131r. Vir\u00fcs\u00fcn \u00fc\u00e7 antijenik tipi vard\u0131r; Tip 1, 2 ve 3. En \u00e7ok Tip 1 infeksiyon yapar. Tipler aras\u0131nda \u00e7arpraz ba\u011f\u0131\u015f\u0131kl\u0131k yoktur. Dolay\u0131s\u0131yla \u00fc\u00e7 kez polyo ge\u00e7irilebilir.<\/p>\n
Vir\u00fcs a\u011f\u0131z yolundan bula\u015f\u0131r. Kulu\u00e7ka s\u00fcresi 5-20 g\u00fcn. Vir\u00fcs yutak ve ince barsakta \u00e7o\u011fal\u0131r. Barsaktan viremi yaparak merkezi sinir sistemine kan yoluyla ula\u015f\u0131r. Vir\u00fcs \u00f6n boynuz h\u00fccrelerini tutar. Bu motor n\u00f6ronlar\u0131n \u00f6l\u00fcm\u00fcyle kaslarda fel\u00e7 meydana gelir. Felcin nedeni kaslar\u0131n de\u011fil sinirlerin infeksiyonudur.<\/p>\n
\u00c7ocuk Felci Belirtileri <\/p>\n
Polyo infeksiyonlar\u0131n\u0131n en az % 90’\u0131 belirtisiz bir \u015fekilde\u00a0 seyreder. Hastal\u0131\u011fa yakalananlarda ate\u015f, ba\u015f\u00a0 ve bo\u011faz a\u011fr\u0131s\u0131, kusma, yorgunluk, boyunda kas\u0131lma ve s\u0131rt a\u011fr\u0131lar\u0131 vard\u0131r. Hastal\u0131\u011f\u0131n ilk g\u00fcnlerinde gerekli tedaviye ba\u015flanmazsa, \u00f6zellikle kol ve bacaklarda fel\u00e7 g\u00f6r\u00fcl\u00fcr. Hastal\u0131\u011f\u0131n ba\u015flang\u0131c\u0131nda hastay\u0131 di\u011fer kimselerden ay\u0131rmak ve yat\u0131rmak gerekir. Polyovir\u00fcs infeksiyonlar\u0131n\u0131n % 1-2’sinde aseptik menenjit geli\u015fir. Bunlarda ense sertli\u011fi ve di\u011fer meninks irritasyon bulgular\u0131 olu\u015fur. Polyovir\u00fcs infeksiyonlar\u0131n\u0131n % 0.1’inde paralitik hastal\u0131k g\u00f6r\u00fcl\u00fcr. Vir\u00fcs \u00f6n boynuz h\u00fccrelerine kan yoluyla ula\u015f\u0131r. Asimetrik yumu\u015fak fel\u00e7lerle seyreder. Tutulan kaslarda his kayb\u0131 olmaz.\u00a0 En \u00e7ok alt ekstremiteler bazen de \u00fcst ekstremiteler tutulur.<\/p>\n
Tan\u0131; <\/p>\n
Enfekte ki\u015filerin kan\u0131nda antikorlar g\u00f6sterilebilir. Bo\u011faz \u00e7alkant\u0131 sular\u0131nda, gaitada ve beyin omurilik s\u0131v\u0131s\u0131nda (BOS) yap\u0131lacak analizlerle vir\u00fcs\u00fcn varl\u0131\u011f\u0131 saptanabilir<\/p>\n
Tedavi: <\/p>\n
\u00d6zg\u00fcn bir tedavisi yoktur. \u015eiddetli hastalarda solunum deste\u011fi gerekebilir. Tedavi i\u00e7in mutlaka doktora ba\u015fvurmak gerekir.<\/p>\n
Komplikasyonlar; <\/p>\n
Beyin veya omurili\u011fin tutulmas\u0131 acil bir durumdur ve fel\u00e7 veya \u00f6l\u00fcmle sonu\u00e7lanabilir. \u00d6l\u00fcmler genelde solunum g\u00fc\u00e7l\u00fc\u011f\u00fcnden meydana gelir. Fel\u00e7, \u00f6l\u00fcmden daha s\u0131k olarak g\u00f6zlenir.<\/p>\n
Korunma; <\/p>\n
\u00e7ocuk felcinden korunmak i\u00e7in Salk a\u015f\u0131s\u0131 veya Sabin a\u015f\u0131s\u0131 yapt\u0131rmak gerekir. Bu a\u015f\u0131n\u0131n ilki \u00e7ocuk 6 ayl\u0131k olmadan \u00f6nce, ikincisi ilk a\u015f\u0131dan 2 Ay sonra, \u00fc\u00e7\u00fcnc\u00fcs\u00fc, ikinci a\u015f\u0131dan 6 ay sonra yap\u0131l\u0131r. 5 ve 15 ya\u015flar\u0131nda da tekrarlan\u0131r. gerekir.<\/p>\n
Salk A\u015f\u0131: Cans\u0131z a\u015f\u0131d\u0131r. Kas i\u00e7ine injekte edilir. Sadece kanda Antikor yap\u0131m\u0131na neden olur. Barsaklarda lokal olarak Ig A yap\u0131m\u0131n\u0131 uyarmad\u0131\u011f\u0131 i\u00e7in koruyuculu\u011fu Canl\u0131 a\u015f\u0131ya g\u00f6re daha d\u00fc\u015f\u00fck orandad\u0131r. Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bask\u0131lanm\u0131\u015f hastalarda g\u00fcvenle kullan\u0131labilir.<\/p>\n
Sabin A\u015f\u0131s\u0131: Canl\u0131 a\u015f\u0131d\u0131r. Barsaklarda \u00e7o\u011fal\u0131r fakat n\u00f6ronlar\u0131 infekte etmez. Oral a\u015f\u0131 oldu\u011fu i\u00e7in kolay uygulanabilir olmas\u0131, kanda antikor yap\u0131m\u0131n\u0131n yan\u0131s\u0131ra barsaklarda \u00e7o\u011falarak antikor sentezini uyarmas\u0131 b\u00f6ylece koruyuculuk oran\u0131n\u0131n \u00f6l\u00fc a\u015f\u0131ya g\u00f6re y\u00fcksek olmas\u0131, d\u0131\u015fk\u0131 ile at\u0131larak topluma yay\u0131lmas\u0131 b\u00f6ylece toplum ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n\u0131n sa\u011flanmas\u0131 \u00f6l\u00fc a\u015f\u0131ya g\u00f6re \u00f6nemli \u00fcst\u00fcnl\u00fckleridir. Canl\u0131 a\u015f\u0131 oldu\u011fu i\u00e7in ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bask\u0131lanm\u0131\u015f hastalarda kullan\u0131lamaz. \u015eehir suyundaki klordan etkilendi\u011fi i\u00e7in oral polyo a\u015f\u0131s\u0131 uygulanan \u00e7ocuklara iki Saat Su i\u00e7irilmemelidir.<\/p>\n
HAZIRLAYAN; Do\u00e7.Dr. O\u011fuz KARABAY<\/p>\n","protected":false},"excerpt":{"rendered":"
Poliovir\u00fcs denilen etkenlerle olu\u015fan beyin veya omurili\u011fin tutulmas\u0131yla karakterize olan ve fel\u00e7 veya \u00f6l\u00fcmle sonu\u00e7lanabilen bula\u015f\u0131c\u0131 bir hastal\u0131kt\u0131r. Vir\u00fcs\u00fcn \u00fc\u00e7 antijenik tipi vard\u0131r; Tip 1, 2 ve 3. En \u00e7ok Tip 1 infeksiyon yapar. Tipler aras\u0131nda \u00e7arpraz ba\u011f\u0131\u015f\u0131kl\u0131k yoktur. Dolay\u0131s\u0131yla \u00fc\u00e7 kez polyo ge\u00e7irilebilir. Vir\u00fcs a\u011f\u0131z yolundan bula\u015f\u0131r. Kulu\u00e7ka s\u00fcresi 5-20 g\u00fcn. Vir\u00fcs yutak ve ince barsakta \u00e7o\u011fal\u0131r. Barsaktan viremi[Devam\u0131n\u0131 Oku…]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22524],"tags":[22981,22979],"_links":{"self":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13169"}],"collection":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/comments?post=13169"}],"version-history":[{"count":0,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13169\/revisions"}],"wp:attachment":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/media?parent=13169"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/categories?post=13169"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/tags?post=13169"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}