Bilirubin safraya renk veren Maddedir. Kanda artt\u0131\u011f\u0131nda cilt, g\u00f6z ak\u0131 ve a\u011f\u0131z i\u00e7i gibi mukoza denilen b\u00f6lgelerde sararma g\u00f6r\u00fcl\u00fcr.<\/p>\n
Bilirubin normal ya\u015fam s\u00fcresini tamamlad\u0131ktan sonra y\u0131k\u0131lan k\u0131rm\u0131z\u0131 k\u00fcreler i\u00e7indeki bir maddenin (hemoglobin) par\u00e7alanmas\u0131 ile olu\u015fur. Bu bilirubin serbest bilirubin\u00a0 (indirekt bilirubin) ismini al\u0131r, kanda Proteine ba\u011flanarak karaci\u011fere ta\u015f\u0131n\u0131r. Karaci\u011fer h\u00fccresi i\u00e7ine al\u0131narak, h\u00fccre i\u00e7inde \u00e7e\u015fitli i\u015flemlerden ge\u00e7er ve ba\u011fl\u0131 bilirubin (direkt bilirubin) haline d\u00f6n\u00fc\u015ft\u00fcr\u00fcl\u00fcr. Karaci\u011fer h\u00fccrelerinde direkt bilirubin \u015feklinde safra kanallar\u0131na sal\u0131n\u0131r ve safra ile barsa\u011fa ge\u00e7er. Barsakta bulunan bakteriler taraf\u0131ndan par\u00e7alan\u0131r, bir k\u0131sm\u0131 tekrar kana ge\u00e7erek karaci\u011fere geri d\u00f6ner, bir k\u0131sm\u0131 da d\u0131\u015fk\u0131 ile at\u0131l\u0131r ve d\u0131\u015fk\u0131ya rengini verir.<\/p>\n
K\u0131rm\u0131z\u0131 k\u00fcrelerin y\u0131k\u0131m\u0131n\u0131n artt\u0131\u011f\u0131 durumlarda kanda serbest bilirubin artarak sar\u0131l\u0131\u011fa neden olur.<\/p>\n
Karaci\u011fer h\u00fccrelerinin hasar\u0131na yol a\u00e7an enfeksiy\u00f6z hastal\u0131klar, ila\u00e7lar, metabolik hastal\u0131klarda \u00f6zellikle direkt bilirubin art\u0131\u015f\u0131 ile sar\u0131l\u0131k g\u00f6r\u00fcl\u00fcr.<\/p>\n
Karaci\u011fer h\u00fccre d\u00fczeyinde bilirubin tutulumunu ya da at\u0131l\u0131m\u0131n\u0131 etkileyen do\u011fumsal hastal\u0131klarda da, karaci\u011fer h\u00fccre d\u00fczeyinde etkilenen b\u00f6lgeye g\u00f6re serbest ya da direkt bilirubin artar ve sar\u0131l\u0131k olu\u015fur.<\/p>\n
Safran\u0131n barsa\u011fa at\u0131l\u0131m\u0131n\u0131n bozuldu\u011fu safra kesesinin olmamas\u0131, safra kesesi ta\u015f\u0131 gibi safra kesesinden safra ak\u0131m\u0131n\u0131n engellendi\u011fi t\u0131kan\u0131kl\u0131k durumlar\u0131nda da \u00f6zellikle kanda direkt bilirubin d\u00fczeyi artar ve sar\u0131l\u0131k g\u00f6r\u00fcl\u00fcr.<\/p>\n
KAYNAKLARGourley G. Bilirubin metabolism Pediatric Gastrointestinal Disease 2004, alan Walker 1344-62. Kliegman RM. Jaundice and hyperbilirubinemia in the newborn.\u00a0 Nelson Textbook of Pediatrics Nelson W.\u00a0 15th ed 1996; 88.3: 493-96. \u00a0<\/p>\n
HAZIRLAYANLAR; Dr. Ceyda TUNA KIRSA\u00c7LIO\u011eLU<\/p>\n","protected":false},"excerpt":{"rendered":"
Bilirubin safraya renk veren Maddedir. Kanda artt\u0131\u011f\u0131nda cilt, g\u00f6z ak\u0131 ve a\u011f\u0131z i\u00e7i gibi mukoza denilen b\u00f6lgelerde sararma g\u00f6r\u00fcl\u00fcr. Bilirubin normal ya\u015fam s\u00fcresini tamamlad\u0131ktan sonra y\u0131k\u0131lan k\u0131rm\u0131z\u0131 k\u00fcreler i\u00e7indeki bir maddenin (hemoglobin) par\u00e7alanmas\u0131 ile olu\u015fur. Bu bilirubin serbest bilirubin\u00a0 (indirekt bilirubin) ismini al\u0131r, kanda Proteine ba\u011flanarak karaci\u011fere ta\u015f\u0131n\u0131r. Karaci\u011fer h\u00fccresi i\u00e7ine al\u0131narak, h\u00fccre i\u00e7inde \u00e7e\u015fitli i\u015flemlerden ge\u00e7er ve ba\u011fl\u0131 bilirubin[Devam\u0131n\u0131 Oku…]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22524],"tags":[23053,23056],"_links":{"self":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13193"}],"collection":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/comments?post=13193"}],"version-history":[{"count":0,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13193\/revisions"}],"wp:attachment":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/media?parent=13193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/categories?post=13193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/tags?post=13193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}