TANIMLAMAB\u00f6brek\u00fcst\u00fc bezinin primer hastal\u0131\u011f\u0131na ba\u011fl\u0131 yetersiz \u00e7al\u0131\u015fmas\u0131 surumudur.B\u00f6brek \u00fcst\u00fc bezinin tamam\u0131n\u0131n veya bir k\u0131sm\u0131n\u0131n hasar\u0131 nedeniyle olu\u015fur. % 80 vakada ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde bozukluk ana sebeptir. T\u00fcberk\u00fcloz ikinci s\u0131radad\u0131r. A\u0130DS, son y\u0131llarda artan nedenlerdendir- S\u00fcrrenal krizi- B\u00f6brek \u00fcst\u00fc bezini yetmezli\u011finin ani ve \u015fiddetle geli\u015fmesi sonucu olu\u015fan ciddi bir taplodur.- Genetik: Genetik ge\u00e7i\u015f ispatlanm\u0131\u015ft\u0131r.- Ya\u015f: Her ya\u015fta g\u00f6r\u00fclebilir- Cinsiyet: kad\u0131nlarda daha fazlad\u0131rBEL\u0130RT\u0130 VE BULGULAR- Kuvvetsizlik- Yorgunluk- Kilo kayb\u0131- Tansiyon d\u00fc\u015fmesi- Deride koyula\u015fma- Zay\u0131flama- Kusma- \u0130shal- So\u011fu\u011fa tolerans\u0131n azalmas\u0131NEDENLER\u0130-Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde bozumaya ba\u011fl\u0131 b\u00f6brek \u00fcst\u00fc yetmezli\u011fi-Sebebi bilinmeyen b\u00f6brek \u00fcst\u00fc bezi yetersiz b\u00fcy\u00fcmesi- Mantar hastal\u0131\u011f\u0131 (histoplazmoz. blastomikozis)- Sarkoidoz hastal\u0131\u011f\u0131\u0131n\u0131n b\u00f6brek \u00fcst\u00fc bezine sirayet etmesi- B\u00f6brek \u00fcst\u00fc bezi i\u00e7ine kanama- Hemokromatozis hastal\u0131\u011f\u0131- Ameliyatla her iki b\u00f6brek \u00fcst\u00fc bezinin al\u0131nmas\u0131.- B\u00f6brek \u00fcst\u00fc bezi t\u00fcm\u00f6rleri- Baz\u0131 hastal\u0131klara(T\u00fcberk\u00fcloz Sarkoidoz vs) ba\u011fl\u0131 b\u00f6brek \u00fcst\u00fc bezinine Protein tabiat\u0131nda Madde birikmesi (Amiloidoz)-A\u0130DSR\u0130SK FAKT\u00d6RLER\u0130- Ba\u011f\u0131s\u0131kl\u0131k sisteminde bozuklu\u011fa ba\u011fl\u0131 B\u00f6brek \u00fcst\u00fc yetmezli\u011finde Aile hikayesi vard\u0131r- Uzun s\u00fcre steroid kullan\u0131m\u0131, ciddi infeksiyon, travma veya cerrahi i\u015flemler sonras\u0131TANI<\/p>\n
LABORATUAR- D\u00fc\u015f\u00fck serum Sodyumu (130 mEq\/ L’den az)- Y\u00fcksek serum potasyumu (5 mEq\/l_’den fazla)- BUN y\u00fckselir- Kortizol d\u00fc\u015fer, renin y\u00fckselir- ACTH seviyesi y\u00fckselir- Orta derecede n\u00f6tropeni\u00d6ZEL TESTLER- Cosyntropin adl\u0131 madde 0,25 mg damardan injekte edilir.Enjeksiyondan \u00f6nce ve sonra kortizol seviyesi \u00f6l\u00e7\u00fcl\u00fcr. Addison hastal\u0131\u011f\u0131nda d\u00fc\u015f\u00fck veya normal bulunur.G\u00d6R\u00dcNT\u00dcLEME- Bat\u0131n bilgisayarl\u0131 tomografisimde b\u00f6brek \u00fcst\u00fc bezlerinde Anormal b\u00fcy\u00fckl\u00fck veya k\u00fc\u00e7\u00fckl\u00fck.- Bat\u0131n grafisinde b\u00f6brek \u00fcst\u00fc bezinin oldu\u011fu b\u00f6lgede kire\u00e7lenme odaklar\u0131.- G\u00f6\u011f\u00fcs grafisi: kalp konturlar\u0131n\u0131n k\u00fc\u00e7\u00fclmesiTEDAV\u0130- Ayaktan tedavi hafi veya orta vakalrda yap\u0131l\u0131r- Adrenal krizde hastaneye yat\u0131rmak \u015fartt\u0131r.GENEL \u00d6NLEMLER. Adrenal yetmezli\u011fi, glukokortikoid ve mineralokortikoid ile tedavi edilirAKT\u0130V\u0130TETolore edebildi\u011fi kadarD\u0130YETSodyumve Potasyum dengesi sa\u011flayacak diyet \u00f6nerilir.TERC\u0130H ED\u0130LEN \u0130LA\u00c7LAR- Hidrokortizon Fludrokortizon Prednisone gibi kortizon preparatlar\u0131 kullan\u0131l\u0131r.- Karaci\u011fer hastal\u0131\u011f\u0131 olanlarda doz azalt\u0131l\u0131r.- Kullan\u0131lan doz yava\u015f yava\u015f azalt\u0131l\u0131r\u00d6NLEM \/ KA\u00c7INMA- Addison hastal\u0131\u011f\u0131n\u0131n \u00f6nlemi bilinmemektedir.BEKLENEN GEL\u0130\u015eME VE PROGNOZ- Uygun tedavide sonu\u00e7lar iyidir- Aktuf t\u00fcberk\u00fcloz ve mantar infeksiyonlar\u0131nda ila\u00e7 tedavisi gerekirKAYNAKLARFelig, P., Baxter, J.D, Broadus, A.E., et al, (eds): Endo\u00e7rinology and metabolism. 2 nd Ed. New York, McGraw-H\u0130II, I987- Hershman, J.M.: Endocrine Pathophysiology: A Patient- Oriented Approach, 3 rd Ed Philadelphia, Lea Febiger, I988Yazar\u0131 Dr. E. Lightner<\/p>\n","protected":false},"excerpt":{"rendered":"
TANIMLAMAB\u00f6brek\u00fcst\u00fc bezinin primer hastal\u0131\u011f\u0131na ba\u011fl\u0131 yetersiz \u00e7al\u0131\u015fmas\u0131 surumudur.B\u00f6brek \u00fcst\u00fc bezinin tamam\u0131n\u0131n veya bir k\u0131sm\u0131n\u0131n hasar\u0131 nedeniyle olu\u015fur. % 80 vakada ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde bozukluk ana sebeptir. T\u00fcberk\u00fcloz ikinci s\u0131radad\u0131r. A\u0130DS, son y\u0131llarda artan nedenlerdendir- S\u00fcrrenal krizi- B\u00f6brek \u00fcst\u00fc bezini yetmezli\u011finin ani ve \u015fiddetle geli\u015fmesi sonucu olu\u015fan ciddi bir taplodur.- Genetik: Genetik ge\u00e7i\u015f ispatlanm\u0131\u015ft\u0131r.- Ya\u015f: Her ya\u015fta g\u00f6r\u00fclebilir- Cinsiyet: kad\u0131nlarda daha fazlad\u0131rBEL\u0130RT\u0130[Devam\u0131n\u0131 Oku…]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22524],"tags":[24122],"_links":{"self":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13586"}],"collection":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/comments?post=13586"}],"version-history":[{"count":0,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/13586\/revisions"}],"wp:attachment":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/media?parent=13586"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/categories?post=13586"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/tags?post=13586"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}