Amerikal\u0131 bilim adamlar\u0131, Alzheimer hastal\u0131\u011f\u0131n\u0131n beyindeki biyolojik belirtisini te\u015fhis etmeyi ba\u015fard\u0131lar. \u015eimdi s\u0131ra testte. Alzheimer’in biyolojik belirtileri olan ADDL isimli proteinler, beyinde ortaya \u00e7\u0131k\u0131yor. Bu proteinlerin, sinir h\u00fccreleri aras\u0131nda ba\u011flant\u0131y\u0131 sa\u011flayan snapslara sald\u0131rd\u0131\u011f\u0131 biliniyor. ADDL’ler ayr\u0131ca, Alzheimer hastalar\u0131n\u0131n beyinlerinde bulunan amyloidbeta’ proteininin yap\u0131\u015fkan plakas\u0131n\u0131n olu\u015fumuna da katk\u0131da bulunuyorlar. ADDL’lerin her biri metrenin 5 milyarda biri uzunlu\u011funda ve sa\u00e7 telinden 20 bin kat daha ince. Bu nedenle normal y\u00f6ntemlerle farkedilmesi imk\u00e1ns\u0131z.Yeni teknikAra\u015ft\u0131rmac\u0131lar yeni test tekni\u011fiyle, Alt\u0131n nano-par\u00e7ac\u0131klar\u0131 ve manyetik nano-par\u00e7ac\u0131klar\u0131, ADDL’lere ba\u011fl\u0131 olan bir antikorla doldurdular. Alt\u0131n nano-par\u00e7ac\u0131\u011f\u0131, DNA’n\u0131n kimyasal bir barkod g\u00f6revi g\u00f6ren k\u0131sm\u0131na eklediler. Her iki par\u00e7ac\u0131\u011f\u0131 da ADDL’lere ekleyebilip, m\u0131knat\u0131s sayesinde omurilik s\u0131v\u0131s\u0131ndan ay\u0131rd\u0131lar.\u015eimdilik sadece beyindeki omurilik s\u0131v\u0131s\u0131nda uygulanan test tekni\u011finin, kanda ve idrarda da ge\u00e7erli olabilece\u011fine inan\u0131l\u0131yor. Testi geli\u015ftiren Northwestern \u00dcniversitesi ekibi, hastal\u0131\u011f\u0131n tedavisi ve ilerlemesinin engellenmesi ad\u0131na da \u00e7al\u0131\u015fmalar yap\u0131yorlar.(H\u00fcrriyet)<\/p>\n","protected":false},"excerpt":{"rendered":"
Amerikal\u0131 bilim adamlar\u0131, Alzheimer hastal\u0131\u011f\u0131n\u0131n beyindeki biyolojik belirtisini te\u015fhis etmeyi ba\u015fard\u0131lar. \u015eimdi s\u0131ra testte. Alzheimer’in biyolojik belirtileri olan ADDL isimli proteinler, beyinde ortaya \u00e7\u0131k\u0131yor. Bu proteinlerin, sinir h\u00fccreleri aras\u0131nda ba\u011flant\u0131y\u0131 sa\u011flayan snapslara sald\u0131rd\u0131\u011f\u0131 biliniyor. ADDL’ler ayr\u0131ca, Alzheimer hastalar\u0131n\u0131n beyinlerinde bulunan amyloidbeta’ proteininin yap\u0131\u015fkan plakas\u0131n\u0131n olu\u015fumuna da katk\u0131da bulunuyorlar. ADDL’lerin her biri metrenin 5 milyarda biri uzunlu\u011funda ve sa\u00e7 telinden 20[Devam\u0131n\u0131 Oku…]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[22524],"tags":[25646,25644,25647,25649],"_links":{"self":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/14163"}],"collection":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/comments?post=14163"}],"version-history":[{"count":0,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/posts\/14163\/revisions"}],"wp:attachment":[{"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/media?parent=14163"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/categories?post=14163"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gncz.net\/index.php\/wp-json\/wp\/v2\/tags?post=14163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}